Deferoxamine-Maleimide (CAS No: 1638156-31-6) is a powerful iron-chelating agent modified with a maleimide group for selective bioconjugation to thiol-containing biomolecules. This compound allows researchers to link deferoxamine to proteins, peptides, or antibodies, creating conjugates that retain strong iron-binding properties.
Applications:
- Chelation Therapy: Useful in designing therapeutics for conditions involving iron overload, as it binds free iron effectively.
- Targeted Imaging: Enables site-specific attachment to biomolecules for imaging applications, especially in MRI where iron-chelated probes enhance contrast.
- Theranostics: Combines diagnostic imaging with iron chelation therapy, creating multifunctional agents for personalized medicine.
- Drug Delivery: Conjugates with drug molecules to deliver targeted iron-chelation therapy while reducing side effects.
Deferoxamine-maleimide supports advanced therapeutic and imaging applications, ideal for preclinical and clinical research in iron metabolism and related diseases.
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