DBCO-NH-PEG5-acid CAS:1870899-46-9 contains a dibenzocyclooctyne (DBCO) functional group, an amine functional group (-NH2), and a carboxylic acid functional group (-COOH) attached to a PEG chain of five ethylene glycol units.
DBCO-NH-PEG5-acid is a popular building block for DBCO derivatization. The acid group can react with amine to form amide bond under coupling conditons in the presence of activators such as EDC, DCC and HATU. DBCO. On the other hand readily react with azide bearing biomolecule through a copper-free click reaction instantly and in high yield.
DBCO-NH-PEG5-acid a valuable tool in the field of pharmaceutical research and development, particularly in the design and synthesis of bioconjugates for drug delivery, diagnostics, and imaging applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
