DBCO-C6-NHS Ester Overview (CAS: 1384870-47-6)
DBCO-C6-NHS Ester is ideal for bioconjugation and click chemistry. It combines a DBCO group for fast, copper-free reactions with azides and an NHS ester that easily attaches to primary amines. Moreover, the C6 spacer adds flexibility, making it perfect for labeling proteins, peptides, and other molecules.
Key Features:
- DBCO Group: Enables fast, selective copper-free click reactions with azides.
- NHS Ester: Quickly binds to primary amines, forming stable connections.
- C6 Spacer: Adds flexibility, improving conjugation ease.
Applications:
- Bioconjugation: Labels proteins, peptides, and antibodies using amine groups.
- Click Chemistry: Links azide-functionalized molecules without needing copper.
- Drug Development: Creates targeted drug conjugates and efficient delivery systems.
Product Citation:
- Sheehy, T.L., Kwiatkowski, A.J., Arora, K., Kimmel, B.R., Schulman, J.A., Gibson-Corley, K.N. and Wilson, J.T., 2024. STING-Activating Polymer–Drug Conjugates for Cancer Immunotherapy. ACS Central Science.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
