Benzoic acid, 4-[3-(trifluoromethyl)-3H-diazirin-3-yl] NHS CAS:87736-89-8 is a chemical compound that is used as a reactive linker molecule in chemical biology and bioconjugation. It is a derivative of benzoic acid, which has been modified with a trifluoromethyl group and an NHS (N-hydroxysuccinimide) ester group.
The NHS ester group is a commonly used reactive group for covalent linking of molecules, such as proteins, to other molecules. When the NHS ester group reacts with a primary amine group on a protein, it forms a stable amide bond.
The trifluoromethyl group in Benzoic acid, 4-[3-(trifluoromethyl)-3H-diazirin-3-yl] NHS can improve the solubility and stability of the linked molecule, as well as enhance its binding affinity to certain targets.
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