BDP FL Tetrazine (CAS: 2042193-77-9) is a bright dye for the FAM (fluorescein) channel, perfect for bioorthogonal labeling. It uses the fast and efficient inverse electron demand Diels-Alder (ied-DA) reaction, where tetrazine reacts with strained dienophiles like trans-cyclooctene, cyclopropene, or cyclooctynes. This reaction provides rapid and selective biomolecule conjugation.
With methyltetrazine, the dye gains more stability in buffers while maintaining its incredibly fast reaction rate. BDP FL Tetrazine efficiently conjugates with strained olefin-bearing molecules, like trans-cyclooctene, for precise labeling.
Key Applications:
- Bioorthogonal Chemistry: Quickly labels biomolecules through ied-DA reactions with strained olefins.
- Live-Cell Imaging: Offers bright green fluorescence for dynamic imaging.
- Bioconjugation: Conjugates proteins, nucleic acids, and other biomolecules with speed and accuracy.
- Diagnostics: Works well in sensitive diagnostic assays.
This dye excels in applications requiring fast, selective labeling and bright fluorescence.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.