Amrubicin (CAS: 110267-81-7) is a synthetic anthracycline and topoisomerase II inhibitor used to treat small cell lung cancer (SCLC). It disrupts DNA replication, causing cancer cell death. Amrubicin is a more effective and less cardiotoxic option compared to traditional anthracyclines like doxorubicin.
Key Information:
- CAS Number: 110267-81-7
- IUPAC Name: (7S,9S)-9-acetyl-7-[(2-deoxy-β-D-erythro-pentopyranosyl)oxy]-6,9,11-trihydroxy-7,8,9,10-tetrahydrotetracene-5,12-dione hydrochloride
- Molecular Formula: C22H24NO9·HCl
- Molecular Weight: 480.90 g/mol
Applications:
- Small Cell Lung Cancer (SCLC): Effective chemotherapy for SCLC and non-small cell lung cancer.
- Topoisomerase II Inhibition: Targets and kills cancer cells by blocking DNA replication.
- Reduced Cardiotoxicity: Offers a safer alternative to other anthracyclines.
Amrubicin Hydrochloride is highly effective in treating small cell lung cancer, offering targeted therapy with fewer side effects.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
