6-Maleimidocaproic acid PFP ester
This product is a heterobifunctional crosslinker featuring a thiol-reactive maleimide and a tetrafluorophenyl (PFP) ester for amine coupling. Its caproic acid spacer enhances flexibility and solubility, making it especially effective for bioconjugation, protein labeling, and drug delivery applications.
Key Features and Benefits:
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Maleimide Group: Selectively reacts with thiols to form stable thioether bonds.
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PFP Ester: Couples efficiently with amines under mild conditions.
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Caproic Spacer: Provides flexibility and improved solubility.
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Orthogonal Reactivity: Supports multifunctional, stepwise conjugation.
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High Purity: Ensures reproducibility in sensitive workflows.
Applications:
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Protein Crosslinking: Links cysteine residues with primary amines.
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Bioconjugation: Builds multifunctional linkers for research and therapeutic use.
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Probe Development: Creates thiol- and amine-reactive diagnostic tools.
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Drug Delivery: Supports stable linker systems for targeted release.
Storage and Handling:
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Storage: Store at –20 °C in a sealed, light- and moisture-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO); prepare fresh solutions to minimize hydrolysis.
This product combines thiol- and amine-reactive groups with a flexible caproic spacer, specifically offering versatility for advanced conjugation and therapeutic development.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
