4-Azidobenzoylamino-PEG2-Biotin CAS:168411-59-4 is a type of small molecule that is commonly used in bioconjugation and biomaterials research. It is composed of several functional groups, including an azide group, a biotin group, and a polyethylene glycol (PEG) spacer.
The azide group is a highly reactive functional group that can undergo click chemistry reactions with various other functional groups, such as alkynes, to form stable covalent linkages. The biotin group is a type of vitamin that is commonly used as a biomolecular tag due to its high affinity for avidin and streptavidin, which are proteins that are commonly used in protein purification and detection. The PEG spacer in 4-Azidobenzoylamino-PEG2-Biotin is used to improve the solubility and stability of the compound in solution, allowing it to be more easily conjugated to other biomolecules.
In bioconjugation, 4-Azidobenzoylamino-PEG2-Biotin can be used as a linker molecule to attach biotin tags to proteins, peptides, or other molecules. The azide group can react with alkyne groups in other molecules to form stable triazole linkages, allowing for the conjugation of biotin tags to specific biomolecules. This enables the creation of biomolecular complexes, allowing for the study of protein-protein interactions or the targeted delivery of therapeutic agents.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.