α-Decitabine CAS:22432-95-7 is a small molecule drug that is used in the treatment of certain types of cancer, including acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS). The drug is composed of several functional groups, including a nucleoside analog group, a deoxyribose sugar group, and a methyl group.
The nucleoside analog group in α-Decitabine is similar in structure to the natural nucleosides found in DNA and RNA, and it works by interfering with the normal process of DNA replication and transcription. Specifically, the drug inhibits the activity of DNA methyltransferases, which are enzymes that add methyl groups to DNA and play a role in gene expression and regulation. By inhibiting DNA methylation, α-Decitabine can help to restore normal gene expression patterns and slow the growth and spread of cancer cells.
The deoxyribose sugar group in α-Decitabine is a key component of the nucleoside analog and is important for the chemical reactivity and solubility of the drug in solution. The methyl group is also important for the activity of the drug, as it plays a role in inhibiting DNA methyltransferases and disrupting DNA replication and transcription.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
