tBu-ester-PEG2-BocNH Tyrosine Methyl Ester is a chemical reagent that is commonly used in peptide synthesis and biomaterials development. This reagent contains a tert-butyl (tBu) protected ester group, a PEG2 (polyethylene glycol with two units) spacer, and a Boc-protected tyrosine methyl ester.
The tert-butyl protected ester group in tBu-ester-PEG2-BocNH Tyrosine Methyl Ester is commonly used in peptide synthesis as a temporary protection for the carboxylic acid group of amino acids. This protection allows for selective reactions at the amine group, and can be easily removed under mild conditions.
The PEG2 spacer in this reagent provides hydrophilicity, flexibility, and biocompatibility, which can reduce non-specific interactions with biomolecules and improve the solubility and stability of the peptide. The Boc-protected tyrosine methyl ester provides a protected tyrosine residue for peptide synthesis.
tBu-ester-PEG2-BocNH Tyrosine Methyl Ester can be used in the solid-phase synthesis of peptides and other biomolecules. The use of this reagent can facilitate the synthesis of peptides with enhanced solubility, biocompatibility, and stability. Additionally, this reagent can be used in the synthesis of peptide-based biomaterials, such as hydrogels and scaffolds.
When working with tBu-ester-PEG2-BocNH Tyrosine Methyl Ester, it is important to handle it with care, as it can be potentially hazardous. Proper protective equipment, including gloves and a lab coat, should be worn, and the reagent should be stored according to the manufacturer’s instructions. Additionally, it is important to follow appropriate disposal procedures for the reagent and any materials contaminated with it.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.