LP01 (CAS: 1799316-64-5) – Advanced Lipid for Drug Delivery
LP01 is a next-generation biodegradable ionizable lipid used in lipid nanoparticle (LNP) technology. It offers superior performance by reducing liver bioaccumulation compared to other ionizable lipids like MC3. With a pKa of 6.1, LP01 is ideal for forming nanoparticles that efficiently deliver a variety of therapeutic agents, including siRNA, mRNA, DNA, and small molecules.
Key Features:
- Biodegradable: Minimizes environmental impact and reduces liver accumulation.
- Ionizable Lipid: Enhances the formation and stability of lipid nanoparticles.
- pKa of 6.1: Optimizes performance in physiological conditions.
Applications:
- Lipid Nanoparticle (LNP) Formulation: Essential for stable and effective LNPs.
- Drug Delivery: Facilitates targeted delivery of nucleotides and small molecules.
- Vaccine Development: Enhances stability and efficacy of mRNA and DNA vaccines.
Advantages:
- Reduced Liver Bioaccumulation: Lowers unwanted accumulation in the liver.
- Efficient Encapsulation: Improves delivery of therapeutic agents.
- Enhanced Cellular Uptake: Increases effectiveness in reaching target cells.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
