DBCO-PEG8-NH-Boc contains two functional groups, including a dibenzocyclooctyne (DBCO) group and a tert-butoxycarbonyl (Boc) protected amine (-NH-Boc) group.
The DBCO group is known for its bioorthogonal reactivity with azide-functionalized molecules, making DBCO-PEG8-NH-Boc a useful tool in the design of targeted drug delivery systems. By covalently attaching azide-containing molecules, such as therapeutic agents or imaging probes, to the PEG chain via the DBCO group, the resulting conjugates can selectively target specific cells or tissues, improving therapeutic efficacy and reducing off-target effects.
DBCO-PEG8-NH-Boc can also be employed as a surface modifier in various biomedical applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.