Thiol-PEG7-Azide CAS:2148986-06-3 is a small molecule linker that contains several functional groups, including a thiol group, a PEG (polyethylene glycol) chain, and an azide group. The thiol group is a sulfur-containing functional group that can react with other thiol-containing molecules, such as cysteine residues in proteins, to form disulfide bonds. The PEG chain improves the solubility, stability, and biocompatibility of the linker, while the azide group can react with alkyne or cyclooctyne groups to form stable triazole linkages.
In biological applications, Thiol-PEG7-Azide can be used to modify the surface of proteins or nanoparticles, allowing for targeted delivery to specific cells or tissues. This modification can improve the pharmacokinetics and efficacy of drugs, as well as reduce their toxicity and immunogenicity. Additionally, it can be used as a starting material for the synthesis of bioconjugates or prodrugs, which are biologically inactive compounds that can be converted into active drugs in the body.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
