TMS-methylcyclopropene-PEG1-OH CAS:1402265-40-0 is a small molecule linker that contains several functional groups, including a TMS (trimethylsilyl) protecting group, a cyclopropene group, a PEG (polyethylene glycol) chain, and a hydroxyl group.
Small molecule linkers are chemical compounds that can be used to join two or more molecules together, often in the context of drug discovery and development. TMS-methylcyclopropene-PEG1-OH can be used to link drugs or imaging agents to other molecules or materials, enabling targeted delivery and imaging in various applications.
The TMS group is often used as a protecting group, which can protect reactive functional groups from undesired reactions during synthesis. The cyclopropene group is a bioorthogonal functional group, which can undergo selective and rapid reaction with tetrazine or trans-cyclooctene groups to form stable covalent bonds. The PEG chain can improve the solubility, biocompatibility, and pharmacokinetics of drugs or imaging agents, while the hydroxyl group can be used for further modification or conjugation.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
