THP-PEG5-Tos CAS:86259-89-4 is a specialized linker molecule composed of a tetrahydropyranyl (THP) functional group, a polyethylene glycol (PEG) chain with five repeating units, and a tosylate (Tos) end group. The THP-protecting group provides stability, the PEG5 spacer imparts hydrophilicity and biocompatibility, while the Tos group enables selective conjugation to target molecules.
THP-PEG5-Tos serves as a versatile and efficient linker for bioconjugation, facilitating the synthesis of targeted drug delivery systems, prodrugs, and antibody-drug conjugates. Its unique combination of functional groups enhances solubility, biocompatibility, and stability of the conjugated molecules, ultimately improving pharmacokinetics and reducing off-target effects, thereby expanding the therapeutic potential of numerous drug candidates.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
