Thiol-PEG3-Azide CAS:1347750-79-1 is a bifunctional thiol peg azide linker featuring a thiol group on one end and an azide group on the other, connected by a triethylene glycol (PEG3) spacer. The thiol group facilitates stable conjugation to maleimide-containing molecules, while the azide group enables click chemistry reactions, such as copper-catalyzed azide-alkyne cycloaddition (CuAAC).
Thiol-PEG3-Azide plays a pivotal role in pharmaceutical research and development by enabling the synthesis of complex drug molecules and bioconjugates. Its unique structure allows for site-specific conjugation of biomolecules, such as proteins and antibodies, with drug payloads or imaging agents. This molecular linker facilitates the development of targeted drug delivery systems, antibody-drug conjugates (ADCs), and theranostics, revolutionizing modern medicine and improving therapeutic efficacy and safety profiles.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.