Thiol-PEG3-Azide (CAS: 1347750-79-1) is a bifunctional linker molecule with a thiol group on one end and an azide group on the other, connected by a triethylene glycol (PEG3) spacer. The thiol end allows stable attachment to maleimide-functionalized molecules, while the azide group enables click chemistry reactions, such as azide-alkyne cycloaddition.
Key Features:
- Bifunctional Reactivity: Combines thiol and azide groups for flexible conjugation.
- PEG3 Spacer: Increases solubility and flexibility, reducing steric hindrance.
- Thiol Group: Forms stable bonds with maleimide groups.
- Azide Group: Ideal for selective click chemistry reactions.
Applications:
- Bioconjugation: Attaches biomolecules (like proteins or peptides) to surfaces or other molecules.
- Drug Development: Used in synthesizing complex drug molecules and bioconjugates.
- Nanotechnology: Functionalizes nanoparticles for targeted delivery.
- Material Science: Helps create materials with specific functional properties.
Storage:
Store at -20°C under argon, keep dry, and protect from light to maintain stability.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
