Thiol-PEG3-alcohol
This product is a bifunctional PEG3 linker with a terminal thiol and hydroxyl group. The PEG3 spacer improves solubility and flexibility, while the thiol enables selective conjugation and the hydroxyl offers a handle for further modification.
Key Features and Benefits:
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Thiol Group: Couples selectively with maleimides, haloacetyls, or forms disulfides.
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Hydroxyl Group: Provides a versatile site for further derivatization or activation.
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PEG3 Spacer: Enhances solubility, flexibility, and reduces steric hindrance.
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High Purity: Ensures reliable results in bioconjugation workflows.
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Compact Design: Short PEG spacer balances hydrophilicity with minimal sterics.
Applications:
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Bioconjugation: Enables thiol- and hydroxyl-based dual functionalization.
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Surface Modification: Functionalizes nanoparticles, hydrogels, or polymers.
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Drug Delivery: PEGylated linker improves solubility and pharmacokinetics.
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Synthetic Chemistry: Useful intermediate for PEG-based scaffold construction.
Storage and Handling:
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Storage: Store at –20 °C in a tightly sealed, light-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) to preserve thiol reactivity.
This product provides dual functionality with thiol and hydroxyl handles in a short PEG spacer, making it especially versatile for controlled conjugation and surface engineering.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
