THAL-SNS-032 is a selective CDK9 degrader PROTAC comprising the cyclin-dependent kinase inhibitor SNS 032 conjugated to the cereblon E3 ligase ligand thalidomide. It inhibited the proliferation of a panel of 11 different leukemia cancer cell lines more effectively than SNS-032.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.