Tetrazine-PEG4-Oxyamine is a versatile bifunctional reagent featuring a tetrazine group for rapid, selective IEDDA reactions with strained alkenes (e.g., TCO) and an oxyamine group for oxime ligation with aldehydes or ketones. The PEG4 spacer enhances solubility, minimizes steric hindrance, and ensures compatibility with biological and chemical systems, making it a valuable tool for a variety of applications.
Features
- Tetrazine Group: Enables fast and selective bioorthogonal conjugation.
- Oxyamine Group: Reacts with aldehydes or ketones for stable oxime linkage.
- PEG4 Spacer: Enhances solubility and reduces steric hindrance.
- High Purity: ≥95% for reliable and reproducible results.
- Biocompatibility: Ideal for use in complex biological environments.
Applications
- Bioconjugation: Dual functionalization of biomolecules with tetrazine and oxyamine chemistry.
- Imaging: Development of fluorescent and radiolabeled probes.
- Diagnostics: Functionalization for biosensors and assay development.
- Therapeutics: Design of drug delivery systems and conjugates.
- Chemical Biology: Studies involving live cells and complex biological systems.
- Material Science: Functionalization of polymers and hydrogels for advanced applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
