Tetrazine-PEG4-Amino-Boc is a versatile reagent featuring a tetrazine group for fast, bioorthogonal IEDDA reactions with strained alkenes (e.g., TCO) and a Boc-protected amino group for controlled deprotection and further functionalization. The PEG4 spacer enhances solubility, reduces steric hindrance, and ensures compatibility in biological and chemical systems.
Features
- Tetrazine Group: Enables rapid and selective IEDDA conjugation.
- Boc-Protected Amino Group: Allows for controlled deprotection and functionalization.
- PEG4 Spacer: Enhances solubility and minimizes steric hindrance.
- High Purity: ≥95% for consistent and reliable results.
- Biocompatibility: Suitable for use in biological and chemical research applications.
Applications
- Bioconjugation: Site-specific modification of biomolecules using IEDDA and amine functionalization.
- Imaging: Development of fluorescent and radiolabeled probes.
- Diagnostics: Functionalization for biosensors and assays.
- Therapeutics: Preparation of drug conjugates and targeted delivery systems.
- Chemical Biology: Studies involving live cells and complex biological environments.
- Material Science: Functionalization of polymers and hydrogels.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
