Tetrazine Oxyamine is a versatile bifunctional reagent combining a tetrazine group for rapid and selective IEDDA reactions with strained alkenes (e.g., TCO) and an oxyamine group for oxime ligation with aldehydes or ketones. Its dual functionality makes it a powerful tool for bioorthogonal labeling, bioconjugation, and chemical biology applications.
Features
- Tetrazine Group: Enables fast, bioorthogonal conjugation via IEDDA reactions.
- Oxyamine Group: Reacts with aldehydes and ketones for stable oxime bonds.
- High Selectivity: Reacts only with target groups, even in complex systems.
- Biocompatibility: Suitable for use in living systems and sensitive environments.
- High Purity: ≥95% for consistent performance.
Applications
- Bioconjugation: Dual labeling of biomolecules with tetrazine and aldehyde/ketone groups.
- Imaging: Site-specific fluorescent or radiolabeling for diagnostics.
- Therapeutics: Development of targeted drug delivery systems.
- Chemical Biology: Studies in live cells or complex biological environments.
- Diagnostics: Functionalization of biomolecules for biosensor development.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
