TCO-PEG1-amine contains a TCO moiety and a free amine. This reagent can be used to derivatize carboxyl acid bearing biomolecules with TCO moiety through a stable amide bond formation in the presence of EDC, DCC and other coupling reagents. The TCO labelled biomolecule can conjugate with a tetrazine bearing biomolecule. The low mass weight adds minimal spacer to modified molecules.
TCO-PEG1-amine is a type of amphiphilic block copolymer used for drug delivery applications. It consists of a hydrophilic polyethylene glycol (PEG) block and a hydrophobic poly(tetramethylene carbonate) (TCO) block, with an amine group at the end. This block copolymer can be used to form micelles that can encapsulate and deliver drugs to target sites in the body.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.