t-Boc-N-Amido-PEG8-acid
This product is a bifunctional PEG8 linker with a Boc-protected amide and a terminal carboxylic acid. The PEG8 spacer enhances solubility and flexibility, while the Boc group offers acid-labile protection for controlled, orthogonal conjugation strategies.
Key Features and Benefits:
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Boc-Protected Amide: Provides stable, acid-labile protection for selective deprotection.
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Carboxylic Acid Group: Couples efficiently with primary amines to form stable amide bonds.
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PEG8 Spacer: Offers moderate chain length for improved hydrophilicity and spacing.
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High Purity: Ensures reproducibility in bioconjugation workflows.
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Orthogonal Reactivity: Supports multistep synthesis and controlled conjugation.
Applications:
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Bioconjugation: Link biomolecules with precise PEG spacing.
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Drug Delivery: Improves solubility and pharmacokinetics of payloads.
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Surface Modification: Functionalize nanoparticles, hydrogels, or polymers.
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Material Science: Incorporate into PEGylated scaffolds for advanced materials.
Storage and Handling:
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Storage: Store at –20 °C in a dry, light-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) to preserve Boc and acid functionality.
This product provides mid-length PEG spacing with Boc protection and acid functionality, making it an especially versatile tool for orthogonal conjugation and synthetic applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
