t-Boc-N-Amido-PEG6-acid
This product is a bifunctional PEG6 linker with a Boc-protected amide and a terminal carboxylic acid. The PEG6 spacer improves solubility and flexibility, while the Boc group provides acid-labile protection for orthogonal conjugation strategies.
Key Features and Benefits:
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Boc-Protected Amide: Enables controlled, selective deprotection.
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Carboxylic Acid Group: Couples efficiently with primary amines.
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PEG6 Spacer: Enhances hydrophilicity and reduces steric hindrance.
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High Purity: Ensures reproducibility in bioconjugation workflows.
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Orthogonal Design: Supports stepwise and selective synthesis.
Applications:
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Bioconjugation: Attach biomolecules through stable amide linkages.
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Drug Delivery: Spacer-linker for improved solubility and pharmacokinetics.
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Surface Functionalization: Modify nanoparticles, polymers, or hydrogels.
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Material Science: Useful in PEGylated polymers and crosslinked materials.
Storage and Handling:
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Storage: Store at –20 °C, protected from moisture and light.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) to maintain reagent stability.
This product offers PEG spacing with Boc protection and acid functionality, making it an especially versatile reagent for controlled bioconjugation and advanced synthetic applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.