Sulfo-NHS (Sulfo-N-Hydroxysuccinimide): Essential Bioconjugation Reagent
Sulfo-NHS (CAS: 106627-54-7) is a highly effective, water-soluble reagent widely used in pharmaceutical research and development. It features a sulfo-N-hydroxysuccinimide group that reacts with primary amines to form stable amide bonds.
Key Features
- Water-Soluble: Ideal for use in aqueous solutions, making it suitable for biological applications.
- Reactive Group: Forms stable amide bonds with primary amines, ensuring reliable attachment of biomolecules.
Applications
- Pharmaceutical Research: Used to modify proteins, antibodies, and peptides, enhancing drug delivery systems and improving pharmacokinetics. Helps create prodrugs and targeted therapies for better treatment outcomes.
- Biosensors and Diagnostics: Facilitates the development of biosensors and diagnostic tests for accurate detection and quantification of biomolecules.
Advantages
- Stable Conjugation: Provides strong and stable bonding of biomolecules.
- Enhanced Drug Delivery: Improves targeting and efficacy of therapeutic molecules.
Sulfo-NHS is crucial for advancing pharmaceutical research and developing innovative therapies and diagnostic tools.
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