(R)-8-Azido-2-(Fmoc-amino)octanoic acid (CAS: 1191429-18-1) is a chiral amino acid derivative featuring an azide group at the 8-position and an Fmoc-protected amine at the 2-position on an octanoic acid backbone. The azide group enables bioorthogonal conjugation via click chemistry, while the Fmoc protection facilitates incorporation into solid-phase peptide synthesis.
Key Features:
- Functional Groups: Azide for click chemistry and Fmoc-protected amine for peptide synthesis.
- Molecular Formula: C₂₄H₂₆N₄O₄
- Molecular Weight: 434.49 g/mol
- Purity: Typically ≥95%
Applications:
- Peptide Synthesis: Incorporation into peptides to introduce an azide functionality for further modification.
- Click Chemistry: Facilitates bioorthogonal conjugation with alkyne-containing molecules.
- Bioconjugation: Enables the attachment of various probes or tags to peptides or proteins.
- Chemical Biology Research: Useful in studying protein interactions and functions through site-specific labeling.
This compound is particularly valuable in applications requiring the introduction of azide functionalities into peptides or proteins, allowing for subsequent modifications via click chemistry.
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