m-PEG12-Propargyl
This product is a monofunctional PEG derivative featuring a propargyl (alkyne) group for click chemistry and a methoxy end for stability. The PEG12 spacer enhances solubility, flexibility, and long spacing, making it especially ideal for bioconjugation, probe development, and drug delivery.
Key Features and Benefits:
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Propargyl Group: Supports CuAAC and SPAAC click chemistry with azides.
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Methoxy End Group: Provides stability and minimizes non-specific reactivity.
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PEG12 Spacer: Improves solubility, hydrophilicity, and steric spacing.
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High Purity: Ensures reproducibility in sensitive workflows.
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Versatile Use: Suitable for protein labeling, probe development, and material science.
Applications:
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Bioconjugation: Click-ready alkyne group enables orthogonal coupling to biomolecules.
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Drug Delivery: PEGylated scaffold enhances solubility and circulation properties.
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Probe Development: Builds functionalized probes for imaging and diagnostics.
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Surface Modification: Functionalizes nanoparticles, polymers, and advanced materials.
Storage and Handling:
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Storage: Store at –20 °C in a tightly sealed, light-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) to maintain alkyne stability.
This product provides a click-ready alkyne handle with a long PEG chain, making it an especially versatile reagent for bioconjugation and material applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
