Phthalimidoxy-PEG2
This product is a PEG-based linker containing a phthalimidoxy protecting group and a PEG2 spacer. It serves as a precursor for hydroxylamine-containing linkers and enables controlled deprotection specifically for use in bioconjugation and chemical biology applications.
Key Features and Benefits
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Phthalimidoxy Group: Protects hydroxylamine functionality for controlled release.
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PEG2 Spacer: Enhances solubility and provides compact flexibility.
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Versatile Precursor: Converts to oxyamine linkers upon deprotection.
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Orthogonal Reactivity: Supports selective chemistry for conjugation workflows.
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High Purity: Ensures reproducibility in synthetic and bioconjugation studies.
Applications
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Bioconjugation: Generates oxyamine linkers for carbonyl–oxime ligation.
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Probe Development: Precursor for multifunctional probes with oxime chemistry.
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Drug Delivery: Serves as an intermediate for PEGylated scaffolds.
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Organic Synthesis: Provides a stable protected form of oxyamine for linker chemistry.
Storage and Handling
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Storage: Keep at –20 °C in a sealed, light- and moisture-protected container.
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Handling: Use anhydrous solvents such as DMF or DMSO to preserve integrity.
This product combines a phthalimidoxy-protected oxyamine with a PEG2 spacer, specifically offering a stable and versatile intermediate for linker synthesis and oxime-based conjugation.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
