PEG12
This product is a polyethylene glycol spacer consisting of 12 ethylene glycol units. Its hydrophilic and flexible structure enhances solubility, reduces steric hindrance, and increases the spacing specifically between conjugated molecules. PEG12 is especially used as a versatile building block in bioconjugation, polymer modification, and drug delivery systems.
Key Features and Benefits
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PEG12 Spacer: Provides moderate chain length for balance between flexibility and compactness.
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Hydrophilic Backbone: Enhances solubility in aqueous and organic solvents.
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Biocompatible Design: Minimizes nonspecific interactions and improves stability of conjugates.
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Synthetic Versatility: Serves as a foundation for functional PEG derivatives.
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High Purity: Produced to ≥95% purity for reproducible results.
Applications
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Bioconjugation: Acts as a spacer between biomolecules, probes, or drug carriers.
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Polymer Chemistry: Integrates into polymers and hydrogels to improve flexibility and water uptake.
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Drug Delivery: Serves as a linker in PEGylated therapeutics to extend circulation time.
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Surface Modification: Functionalizes nanoparticles and materials to increase biocompatibility.
Storage and Handling
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Storage: Keep at –20 °C in a sealed container, protected from light and moisture.
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Handling: Use freshly prepared solutions; avoid repeated freeze–thaw cycles.
This product provides a balance of chain length, solubility, and flexibility, making it an especially excellent intermediate for PEGylation, conjugation, and advanced material applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
