p-NH₂-Bn-PCTA
This product is a bifunctional chelator containing a para-aminobenzyl group and a PCTA (1,4,7-triazacyclononane-triacetic acid) macrocycle. It enables stable radiometal chelation and amine conjugation, specifically offering compact structure and dual functionality for imaging and therapy.
Key Features and Benefits
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PCTA Macrocycle: Provides strong, stable chelation of radiometals such as Ga(III) and In(III).
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Para-Amino Group: Couples efficiently with carboxyls, NHS esters, or activated linkers.
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Benzyl Spacer: Enhances stability and accessibility of reactive groups.
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Dual Reactivity: Combines metal chelation with amine conjugation.
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High Purity: Ensures reproducibility in radiochemistry and bioconjugation workflows.
Applications
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Radiochemistry: Chelates radiometals for PET, SPECT, and therapeutic applications.
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Bioconjugation: Links chelator moieties to biomolecules via amine coupling.
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Probe Development: Builds radiolabeled probes for diagnostics and imaging.
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Drug Delivery: Supports design of radiometal-based therapeutics.
Storage and Handling
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Storage: Store at –20 °C in a sealed, light- and moisture-protected container.
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Handling: Use anhydrous solvents; avoid prolonged exposure to moisture.
This product integrates stable PCTA chelation with para-amino reactivity, specifically enabling radiometal labeling and bioconjugation in one compact scaffold.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
