OPSS-PEG-NH2, MW 2K is a high-quality and versatile biocompatible linker with a molecular weight of 2,000 Da. The polymer consists of three functional components: OPSS is a reactive group that can form disulfide bonds upon reacting with thiol-containing molecules. This reversible disulfide linkage allows for stimuli-responsive release, making it useful in the controlled release of bioactive compounds.
PEG is a biocompatible, water-soluble polymer composed of repeating ethylene glycol units.NH2 is a functional group that can participate in various chemical reactions, enabling conjugation with other biomolecules such as peptides, proteins, and small molecules.
OPSS-PEG-NH2, MW 2K’s unique combination of functional groups renders it an ideal linker for creating advanced drug delivery systems and functionalizing surfaces for tissue engineering. Its OPSS group allows for the conjugation of thiol-containing molecules via stable, reversible disulfide bonds, facilitating targeted and controlled release under specific physiological conditions. The PEG component imparts biocompatibility, water solubility, and stealth-like properties, helping to evade the immune system and prolong circulation time. Finally, the NH2 group enables the attachment of various bioactive molecules for targeted delivery, imaging, or regenerative medicine applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.