OH-PEG-SC, MW 6K
This product is a bifunctional polyethylene glycol (PEG) derivative containing a terminal hydroxyl group and a succinimidyl carbonate (SC). With a molecular weight of 6,000 Da, it specifically enables amine conjugation, PEGylation, and bioconjugation while improving solubility and stability.
Key Features and Benefits
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Hydroxyl Group: Provides a handle for further derivatization or modification.
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Succinimidyl Carbonate (SC): Reacts efficiently with primary amines to form stable carbamate bonds.
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6K PEG Backbone: Improves solubility, biocompatibility, and circulation half-life.
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Dual Functionality: Combines hydroxyl versatility with amine-reactive SC chemistry.
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High Purity: Ensures reproducibility in PEGylation and bioconjugation workflows.
Applications
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PEGylation: Extends half-life and stability of proteins, peptides, and drugs.
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Bioconjugation: Couples PEG scaffolds to amine-containing biomolecules.
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Drug Delivery: Improves solubility and circulation time of therapeutics.
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Material Science: Functionalizes surfaces and polymers with PEG.
Storage and Handling
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Storage: Store at –20 °C in a sealed, light- and moisture-protected container.
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Handling: Dissolve in appropriate solvents; avoid prolonged moisture exposure.
This product integrates hydroxyl flexibility with SC chemistry in a medium-chain PEG scaffold, specifically offering solubility, stability, and reliable conjugation capability.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
