OH-PEG-SC / HO-PEG-NHS Ester, MW 1000 Overview
OH-PEG-SC or HO-PEG-NHS Ester is a PEG molecule with an NHS ester on one end and a hydroxyl group on the other. The NHS ester reacts quickly with amines, creating stable bonds. The PEG chain (MW 1000) improves solubility and biocompatibility, making it useful in bioconjugation, drug delivery, and surface coating.
Key Features:
- NHS Ester: Reacts quickly with amines for strong, stable bonds.
- PEG Spacer (MW 1000): Improves water solubility and reduces protein binding.
- Hydroxyl Group: Can be used for more modifications or left unreacted.
Applications:
- Bioconjugation: Links proteins, peptides, or other amine-containing molecules.
- Drug Delivery: Improves the solubility and stability of drugs.
- Surface Coating: Creates biocompatible, non-stick surfaces on nanoparticles or medical devices.
Advantages:
- Fast Reaction: NHS ester ensures quick and reliable bonding with amines.
- Better Solubility: The PEG chain helps with water solubility and reduces aggregation.
- Versatile: Useful for many fields like drug development, bioconjugation, and surface modifications.
OH-PEG-SC / HO-PEG-NHS Ester is great for researchers needing efficient solutions in bioconjugation, drug delivery, or surface modifications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.