Norbornene-PEG7-Pyrene
This product is a multifunctional PEG linker containing a norbornene group, a PEG7 spacer, and a fluorescent pyrene moiety. It specifically enables bioorthogonal tetrazine click chemistry and fluorescence-based detection in a soluble, flexible scaffold.
Key Features and Benefits
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Norbornene Group: Reacts rapidly with tetrazines via IEDDA click chemistry.
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Pyrene Moiety: Provides strong fluorescence for detection and imaging.
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PEG7 Spacer: Improves solubility and minimizes steric hindrance.
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Dual Functionality: Combines bioorthogonal click chemistry with fluorescent labeling.
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High Purity: Ensures reproducibility in conjugation and imaging workflows.
Applications
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Bioconjugation: Links tetrazine-modified molecules with fluorescent probes.
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Probe Development: Builds multifunctional probes for imaging and diagnostics.
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Drug Delivery: Provides PEG scaffolds with orthogonal click and fluorescent handles.
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Material Science: Functionalizes nanoparticles and polymers with click and fluorescent properties.
Storage and Handling
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Storage: Store at –20 °C in a sealed, light- and moisture-protected container.
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Handling: Use anhydrous solvents such as DMF or DMSO; avoid prolonged exposure to moisture and light.
This product integrates bioorthogonal norbornene click chemistry with pyrene fluorescence in a PEG7 scaffold, specifically offering dual-functionality for bioconjugation and imaging.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
