N,N-Bis(PEG2-azide)-N-Boc
This product is a multifunctional PEG-based linker featuring two terminal azides, a Boc-protected amine, and short PEG2 spacers. The azides enable copper-catalyzed or copper-free click chemistry, while the Boc group provides acid-labile protection, making this reagent highly versatile for orthogonal synthesis and bioconjugation.
Key Features and Benefits:
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Dual Azides: Support CuAAC and SPAAC click chemistry with alkyne partners.
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Boc-Protected Amine: Provides stability and controlled deprotection.
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PEG2 Spacers: Enhance solubility and reduce steric hindrance.
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High Purity: Ensures reproducibility in sensitive workflows.
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Orthogonal Design: Enables multifunctional and stepwise conjugation strategies.
Applications:
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Bioconjugation: Attach biomolecules using click chemistry and amine coupling.
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Drug Delivery: Useful for linker-payload designs requiring orthogonal handles.
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Surface Modification: Functionalize nanoparticles, hydrogels, and polymers.
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Synthetic Chemistry: Versatile intermediate for PEGylated scaffold construction.
Storage and Handling:
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Storage: Store at –20 °C, protected from moisture and light.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) to maintain azide and Boc stability.
This product combines dual azide reactivity with a protected amine, making it an especially efficient linker for multifunctional and orthogonal bioconjugation strategies.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
