NH-bis(PEG4-Boc)
This product is a multifunctional PEG derivative containing a central amine substituted with two PEG4 chains, each capped by a Boc-protected amine. This design provides excellent solubility, extended spacing, and orthogonal protection, making it especially useful in bioconjugation, drug delivery, and synthetic chemistry.
Key Features and Benefits:
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Central Amine Core: Provides a branching scaffold for dual PEG arms.
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Boc-Protected Amines: Acid-labile groups support orthogonal deprotection.
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PEG4 Spacers: Enhance solubility, hydrophilicity, and steric accessibility.
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Orthogonal Reactivity: Enables stepwise, controlled conjugation strategies.
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High Purity: Ensures reproducibility in advanced workflows.
Applications:
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Bioconjugation: Builds multifunctional PEGylated conjugates with controlled protection.
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Drug Delivery: Enhances solubility and provides orthogonal synthetic handles.
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Probe Development: Creates protected intermediates for diagnostic probe assembly.
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Synthetic Chemistry: Useful as a branching intermediate in complex linker design.
Storage and Handling:
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Storage: Store at –20 °C in a tightly sealed, moisture- and light-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO); avoid premature Boc deprotection.
This product combines dual Boc-protected PEG arms with a central amine scaffold, specifically offering solubility, orthogonal control, and versatility in advanced synthesis and conjugation.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
