NH-bis(PEG3-azide) CAS: 1258939-39-7 is a bifunctional molecule features two azide functional groups linked by a polyethylene glycol (PEG) spacer, comprising three ethylene glycol units. The azide moieties provide reactive sites for bioorthogonal click chemistry, while the hydrophilic PEG spacer enhances aqueous solubility, reduces immunogenicity, and increases biocompatibility.
As a result, NH-bis(PEG3-azide) is ideal for the site-specific conjugation of biomolecules, such as proteins, peptides, and nucleic acids. It is commonly utilized in the creation of bioconjugates for targeted drug delivery, controlled release systems, and imaging probes. Additionally, it is instrumental in the development of antibody-drug conjugates (ADCs), which are essential in modern oncology therapies.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.