N-(Trifluoroacetyl)-beta-alanine acid chloride
This product is a reactive intermediate containing a trifluoroacetyl-protected amine, a β-alanine backbone, and an acid chloride. It enables efficient coupling reactions, specifically providing fluorinated control and high reactivity for synthetic and bioconjugation applications.
Key Features and Benefits
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Trifluoroacetyl Group: Provides electron-withdrawing protection for controlled reactivity.
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Acid Chloride: Couples rapidly with amines, alcohols, or thiols to form stable bonds.
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β-Alanine Core: Adds structural flexibility and hydrophilic character.
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Fluorinated Scaffold: Enhances stability and modulates electronic properties.
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High Purity: Ensures reproducibility in demanding synthesis workflows.
Applications
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Organic Synthesis: Serves as a versatile intermediate for fluorinated derivatives.
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Bioconjugation: Couples biomolecules through rapid acid chloride reactivity.
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Probe Development: Provides fluorinated handles for chemical biology tools.
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Medicinal Chemistry: Supports design of fluorinated linkers or prodrugs.
Storage and Handling
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Storage: Store at –20 °C in a sealed, moisture-protected container.
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Handling: Use anhydrous solvents under inert atmosphere; avoid prolonged air or moisture exposure.
This product integrates trifluoroacetyl protection with acid chloride reactivity, specifically offering a highly reactive scaffold for synthesis and conjugation.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
