N-(PFP ester-PEG3)-N-bis(PEG3-Azide)
N-(PFP ester-PEG3)-N-bis(PEG3-Azide) is an advanced bifunctional PEGylated reagent used in biochemical and pharmaceutical applications. It features a stable PFP ester group, which provides greater reliability compared to NHS esters, and two PEG3-azide groups that enhance the drug-to-antibody ratio (DAR). This innovative structure ensures efficient bioconjugation, making it ideal for both therapeutic and diagnostic applications, and improves the efficacy and precision of conjugation.
Key Features
- PFP Ester Group: Provides superior stability compared to NHS esters, ensuring more reliable conjugation.
- PEG3 Chains: Enhance solubility and flexibility of the conjugated molecules.
- Bis Azide Groups: Increase the drug-to-antibody ratio (DAR) for better targeting and effectiveness.
Applications
- Bioconjugation: Ideal for attaching biomolecules with improved stability and performance.
- Drug Development: Enhances targeted delivery systems by increasing DAR, leading to better therapeutic outcomes.
- Imaging: Facilitates precise labeling for efficient tracking and visualization of biomolecules.
Advantages
- Enhanced Stability: PFP ester ensures more stable and reliable conjugation compared to traditional NHS esters.
- Increased DAR: The bis azide groups boost the drug-to-antibody ratio, optimizing therapeutic efficacy.
- Efficient Labeling: Azide groups enable effective click chemistry for accurate and specific bioconjugation.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
