N-Fmoc-N’-(azido-PEG4)-L-Lysine is a versatile amino acid derivative with an Fmoc-protected α-amine and an azide-functionalized PEG4 chain on the ε-amino group of L-lysine. The Fmoc group supports solid-phase peptide synthesis, while the azide group enables bioorthogonal conjugation through click chemistry.
Key Features:
- Functional Groups: Fmoc-protected α-amine for peptide synthesis and azide-functionalized ε-amine for click chemistry.
- Molecular Formula: C₂₆H₃₃N₅O₆
- Molecular Weight: 511.58 g/mol
- Purity: Typically ≥95%
Applications:
- Peptide Synthesis: Incorporates into peptides to introduce an azide group for later functionalization.
- Click Chemistry: Reacts with alkyne-containing molecules for efficient bioconjugation.
- PROTAC Development: Serves as a linker in proteolysis-targeting chimera (PROTAC) synthesis for targeted protein degradation.
- Bioconjugation: Attaches probes or tags to biomolecules for research and diagnostic applications.
- Chemical Biology Research: Enables site-specific labeling and studying protein interactions.
This compound is ideal for developing multifunctional biomolecules, including PROTACs, peptides, and protein-labeling probes.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
