N-Boc-PEG1-bromide
This product is a heterobifunctional PEG linker containing a Boc-protected amine, a PEG1 spacer, and a reactive bromide group. It specifically enables orthogonal amine deprotection and nucleophilic substitution, offering solubility, compact design, and versatile reactivity.
Key Features and Benefits
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Boc-Protected Amine: Allows selective deprotection for orthogonal conjugation.
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Bromide Group: Functions as a leaving group for nucleophilic substitution.
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PEG1 Spacer: Provides compact spacing and solubility.
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Dual Reactivity: Combines orthogonal amine chemistry with substitution capability.
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High Purity: Ensures reproducibility in sensitive workflows.
Applications
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Bioconjugation: Links biomolecules through substitution or amine coupling.
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Probe Development: Builds multifunctional probes with orthogonal handles.
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Drug Delivery: Provides PEG scaffolds with solubility and dual reactivity.
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Organic Synthesis: Serves as an intermediate for custom linker design.
Storage and Handling
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Storage: Store at –20 °C in a sealed, light- and moisture-protected container.
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Handling: Use anhydrous solvents such as DMF or DMSO; avoid prolonged exposure to moisture.
This product integrates Boc-protected amine chemistry with bromide substitution in a PEG1 scaffold, specifically offering compact and orthogonal reactivity.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
