N’-Boc-N-(Gly-Oleoyl)-Lys
This product is a Boc-protected lysine derivative with a glycine–oleoyl modification. The Boc group protects the lysine amine for controlled deprotection. Its amphiphilic design specifically supports lipidation chemistry, peptide modification, membrane anchoring, and bioconjugation research.
Key Features and Benefits
-
Boc Protection: Provides temporary amine protection, enabling controlled synthetic steps and selective deprotection.
-
Gly-Oleoyl Modification: Introduces a hydrophobic oleoyl chain via glycine linkage for membrane interactions and lipidation chemistry.
-
Amphiphilic Design: Combines hydrophobic lipid chain and hydrophilic amino acid scaffold for self-assembly and bioconjugation versatility.
-
Peptide Compatibility: Suitable for solid-phase and solution-phase peptide synthesis workflows.
-
High Purity: Manufactured to ≥95% purity to ensure reliable performance in research applications.
Applications
-
Peptide Lipidation: Facilitates synthesis of lipidated peptides for stability, bioavailability, and cell-penetration enhancement.
-
Drug Delivery Research: Serves as a building block for lipid–peptide conjugates in nanocarrier and micelle formation.
-
Bioconjugation: Supports functionalization of peptides, proteins, or biomaterials with lipid anchors for membrane binding.
-
Membrane Interaction Studies: Useful for exploring lipid–protein interactions and amphiphilic system design.
Storage and Handling
-
Storage: Keep at –20 °C in a tightly sealed container, protected from moisture and light.
-
Handling: Use under inert atmosphere when possible; deprotect Boc group with mild acidic conditions before further derivatization.
This product integrates Boc-protected lysine chemistry with lipid modification, specifically offering a versatile tool for peptide engineering, drug delivery research, and bioconjugation strategies.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
