Methyltetrazine-NHS ester CAS:1644644-96-1 is a versatile bioconjugation reagent, characterized by a reactive methyltetrazine moiety and an N-hydroxysuccinimide (NHS) ester group. The methyltetrazine group facilitates rapid and selective bioorthogonal ligation via inverse electron-demand Diels-Alder (iEDDA) reactions, while the NHS ester enables efficient conjugation to amine-containing biomolecules such as proteins, peptides, and nucleic acids.
In pharmaceutical research and development, Methyltetrazine-NHS ester plays a pivotal role in constructing bioconjugates for targeted drug delivery, diagnostic imaging, and bioorthogonal chemistry applications. Its unique reactivity allows for the creation of stable, site-specific conjugates with minimal off-target effects, thus enabling researchers to develop innovative therapeutics and diagnostic tools with enhanced precision, safety, and efficacy.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.