Methylcyclopropene-PEG3-NHBoc is a small molecule linker that is used in the field of bioconjugation and drug delivery. It contains several functional groups, including a cyclopropene group, a PEG (polyethylene glycol) chain, and an N-tert-butoxycarbonyl (NHBoc) group.
The cyclopropene group is a highly reactive functional group that can react with a wide range of functional groups, including tetrazine, trans-cyclooctene, and norbornene. This reactivity allows for the covalent attachment of the linker to other molecules, such as proteins, peptides, or nanoparticles, enabling targeted drug delivery to specific cells or tissues.
The PEG chain in Methylcyclopropene-PEG3-NHBoc improves the solubility and biocompatibility of the linker, while the NHBoc group can be used to protect the amine group from unwanted reactions during the conjugation process. The linker can be easily deprotected by treatment with an acid, releasing the amine group for further conjugation reactions.
Methylcyclopropene-PEG3-NHBoc is a valuable tool in the field of bioconjugation and drug delivery, enabling the development of targeted therapeutics for various diseases. Its unique combination of functional groups provides a high degree of flexibility in designing and synthesizing drug conjugates, and its reactivity and stability make it an important component of modern pharmaceutical research.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.