Mal-PEG4-Amine TFA Salt
CAS: 2221042-92-6
Description:
Mal-PEG4-amine TFA salt is a bifunctional linker containing a maleimide group, a PEG4 spacer, and a terminal amine in its TFA (trifluoroacetic acid) salt form. The maleimide group reacts specifically with thiol groups, while the amine can conjugate with carboxyl and other reactive groups, making it ideal for versatile bioconjugation applications.
Key Features:
- Maleimide Group: Enables specific binding to thiol-containing molecules, such as cysteine residues in proteins.
- PEG4 Spacer: Increases solubility and flexibility, reducing steric hindrance in conjugation.
- Terminal Amine: Reacts with carboxyl and other functional groups, broadening the range of conjugation targets.
Applications:
- Bioconjugation: Links proteins, peptides, and other biomolecules through thiol and amine chemistries.
- Drug Delivery: Facilitates stable attachment of drugs to biomolecules for targeted delivery.
- Protein Labeling: Useful in modifying proteins for research, diagnostics, and therapeutic applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
