Mal-PEG-OH, MW 7.5K is a heterobifunctional maleimide PEG hydroxyl product commonly used as a crosslinker or a spacer between two different chemical entities. It can be further derivatized by hydroxyl functionalization. Maleimide reacts with cysteine or thiol molecules to form thioether bonds. The PEG moiety in the heterofunctional PEG derivatives provides water solubility, biocompatibility and flexibility. Applications are particularly suitable for the development of antibody drug conjugates (ADCs).
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.