Mal-hexyoxyamine
This product is a bifunctional linker containing a maleimide group and a terminal oxyamine connected via a hexyl spacer. It enables selective thiol coupling through maleimide chemistry and carbonyl conjugation through oxime ligation, specifically offering dual orthogonal reactivity for bioconjugation.
Key Features and Benefits
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Maleimide Group: Couples selectively with thiols to form stable thioether bonds.
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Oxyamine Group: Reacts with aldehydes and ketones to form oxime linkages.
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Hexyl Spacer: Provides flexibility while maintaining compact molecular design.
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Dual Reactivity: Combines thiol-selective and carbonyl-targeting chemistries.
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High Purity: Ensures reliable performance in advanced bioconjugation workflows.
Applications
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Bioconjugation: Links thiol-containing and carbonyl-containing biomolecules.
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Probe Development: Builds multifunctional probes with orthogonal reactive handles.
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Drug Delivery: Provides cleavable and versatile scaffolds for targeted conjugates.
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Material Science: Functionalizes polymers or nanoparticles with thiol and oxime chemistry.
Storage and Handling
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Storage: Keep at –20 °C in a sealed, light- and moisture-protected container.
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Handling: Use anhydrous solvents such as DMF or DMSO; avoid prolonged exposure to moisture.
This product integrates maleimide–thiol coupling with oxyamine–carbonyl conjugation in a hexyl scaffold, specifically providing a versatile dual-reactive linker for synthetic chemistry and bioconjugation applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
