m-PEG8-acid
This product is a high-purity methoxy-PEG reagent with a terminal carboxylic acid group on a PEG8 spacer, specifically providing solubility, flexibility, and a reactive site for conjugation.
Key Features and Benefits
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Methoxy Group – Provides stability and minimizes non-specific interactions.
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Carboxylic Acid Group – Enables amide bond formation with primary amines.
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PEG8 Spacer – Enhances solubility, reduces steric hindrance, and improves molecular accessibility.
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High Purity – Suitable for bioconjugation, drug delivery, and surface modification.
Applications
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PEGylation of proteins, peptides, or small molecules
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Amide coupling for drug delivery and probe functionalization
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Surface modification for improved biocompatibility
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Linker for antibody–drug conjugates and diagnostics
Storage & Handling
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Storage: Store at –20 °C, dry, and protected from light.
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Use: Dissolve in anhydrous solvents (e.g., DMF, DMSO). Avoid repeated freeze–thaw cycles.
This product provides a terminal carboxyl group on a PEG8 chain, enabling stable amide coupling while improving solubility and reducing steric hindrance. It is an especially versatile tool for PEGylation and bioconjugation applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
