m-PEG7-Ms
This product is a monofunctional PEG linker featuring a mesyl (methanesulfonyl) reactive group and a PEG7 spacer. The mesyl group serves as an excellent leaving group, specifically enabling nucleophilic substitution for custom PEG modifications and linker synthesis.
Key Features and Benefits
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Mesyl Group: Highly reactive leaving group for substitution with amines, thiols, or alkoxides.
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PEG7 Spacer: Provides solubility, flexibility, and reduced steric hindrance.
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Reactive Intermediate: Versatile precursor for a range of PEG-based derivatives.
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Compact Design: Balances solubility with manageable molecular size.
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High Purity: Supports reproducibility in synthetic and bioconjugation workflows.
Applications
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Organic Synthesis: Generates functional PEG derivatives via mesyl substitution.
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Bioconjugation: Builds PEGylated linkers for proteins, peptides, or small molecules.
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Material Science: Introduces PEG functionality into polymers and nanostructures.
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Drug Delivery: Prepares PEG scaffolds for improved solubility and drug stability.
Storage and Handling
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Storage: Keep at –20 °C in a sealed, light- and moisture-protected container.
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Handling: Use anhydrous solvents such as DMF or DMSO to maintain reactivity.
This product integrates a mesyl leaving group with a PEG7 spacer, specifically offering a reactive and soluble intermediate for linker synthesis, bioconjugation, and material applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
