m-PEG4-DBCO
This product is a monofunctional PEG linker featuring a dibenzocyclooctyne (DBCO) group connected through a PEG4 spacer. It enables rapid, copper-free click reactions with azides while offering excellent solubility and biocompatibility for biological and material science applications.
Key Features and Benefits
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DBCO Group: Supports strain-promoted azide–alkyne cycloaddition (SPAAC) without copper.
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PEG4 Spacer: Enhances solubility and reduces steric hindrance.
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Bioorthogonal Reactivity: Compatible with live-cell labeling and biomolecule conjugation.
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Compact Design: Provides accessibility with minimal steric effects.
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High Purity: Ensures reproducibility in sensitive bioconjugation workflows.
Applications
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Bioconjugation: Attaches azide-labeled proteins, peptides, or nucleic acids.
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Probe Development: Builds copper-free clickable probes for imaging and diagnostics.
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Drug Delivery: Constructs PEGylated scaffolds with bioorthogonal reactivity.
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Material Science: Functionalizes surfaces and polymers with DBCO–azide chemistry.
Storage and Handling
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Storage: Keep at –20 °C in a sealed, light- and moisture-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO); avoid prolonged exposure to moisture.
This product combines copper-free click reactivity with a PEG4 spacer, specifically providing a soluble and versatile tool for advanced bioconjugation and synthetic applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
